HIF at a glance.

The transcription of Hypoxia-inducible factors (hif-1, hif-2) during normal development of Beluga sturgeon (Huso huso Linnaeus, 1758)

In the present study, the levels of the hypoxia-inducible factors (hif-1, hif-2) transcripts were evaluated during development of an ancient fish species, Beluga sturgeon (Huso huso) in a normal oxygen environment. The transcripts of hif-1, hif-2 were detected in all developmental time-points of H. huso from embryos to juvenile fish. Changes in normalized hif-1, hif-2 mRNA expression by using t...

Chemicals and Infertility at a Glance

The University of Social Welfare and Rehabilitation Sciences at a Glance

Cancer metastasis at a glance: A brief view of Breast Cancer Brain Metastasis

Cancer initiation and progression is a challenging scenario through developmental processes, which may be more complicated by occurrence of metastasis. Basically, diverse genetic alterations, including mutations, formation of truncated proteins and related pathways play key roles either in diagnosis or the most influential therapeutic purposes. ...

Effect of High-Intensity Interval Training (HIIT) on Hypoxia-Inducible Factor-1 Alpha (HIF-1α) Gene Expression in Heart Tissue and Insulin Resistance Index in Type 2 Diabetic Rats

 Background and Aim: One of the most common metabolic diseases is diabetes with hyperglycemic properties and endogenous insulin dysfunction. This study aimed to evaluate the effect of 10 weeks HIIT on HIF-1α gene expression in heart tissue of rats with type 2 diabetes. Methods: In this experimental study, 36 Wister rats with a mean weight of 200±58g were randomly assigned to control, diabetic,...